Chicken CTTN1/ Src substrate protein p85 CLIA Kit

货号:

商标:

EIAab^®

监管等级:

RUO

别名:

Cortactin, p80, EMS1, P85.25

检测方法:

CLIA

特异性:

Natural and recombinant chicken Src substrate protein p85

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

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Chicken CTTN1 CLIA Kit

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通用注释

亚单元:

N/A

功能:

Contributes to the organization of the actin cytoskeleton and cell shape (By similarity). Plays a role in the formation of lamellipodia and in cell migration (By similarity). Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones, and may play a role in the regulation of neuronal spine density (By similarity). Plays a role in focal adhesion assembly and turnover (By similarity). Plays a role in intracellular protein transport and endocytosis, and in modulating the levels of potassium channels present at the cell membrane (By similarity). Plays a role in endocytosis via clathrin-coated pits.

亚细胞位置:

Cell membrane Endoplasmic reticulum Cytoplasm Cytoskeleton Cell projection Lamellipodium Cell projection Ruffle Cell projection Dendritic spine Cell projection Dendrite Cell projection Cell junction Membrane Clathrin-coated pit Cell junction Focal adhesion Cell projection Podosome Colocalizes transiently with PTK2/FAK1 at focal adhesions (By similarity). Associated with membrane ruffles and lamellipodia. In normal cells, probably in association with the plasma membrane and possibly the endoplasmic reticulum (PubMed:1922035). p80/85 colocalizes with F-actin in peripheral extensions of normal cells and rosettes (podosomes) of src-transformed cells. p80/85 probably associates with components of the cytoskeleton. In response to neuronal activation by glutamate, redistributes from dendritic spines to the dendritic shaft (By similarity).

数据库链接

UniGene:

Gga.37455

SMR:

Q01406

STRING:

9031.ENSGALP00000012463

KEGG:

gga:396455

Pfam:

PF02218

Uniprot: