Rat Ighmbp2/ DNA-binding protein SMUBP-2 CLIA Kit

货号:

商标:

EIAab^®

监管等级:

RUO

别名:

ATP-dependent helicase IGHMBP2, Antifreeze enhancer-binding protein ortholog, AEP, Smbp2

检测方法:

CLIA

特异性:

Natural and recombinant rat DNA-binding protein SMUBP-2

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Neurosciences

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Rat Ighmbp2 CLIA Kit

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通用注释

亚单元:

Homooligomer. Interacts with RUVBL1, RUVBL2, GTF3C1 and ABT1. Is part of large cytosolic ribonucleoprotein complexes. Associates with the ribosomes.

功能:

5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin II gene RIPE3B enhancer region (By similarity). May be involved in translation. DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region. Preferentially binds to the 5'-GGGCT-3' motif. Interacts with tRNA-Tyr.

亚细胞位置:

Nucleus Cytoplasm Cell projection Axon Colocalizes with the translation initiation factor EIF4G2.

数据库链接

UniGene:

Rn.23984

STRING:

10116.ENSRNOP00000018487

KEGG:

rno:29532

Pfam:

PF01424

Uniprot: