HNRNPA2B1 (基因名), Heterogeneous nuclear ribonucleoproteins A2/B1 (蛋白名), roa2_human.
产品名称:
Human HNRNPA2B1/ Heterogeneous nuclear ribonucleoproteins A2/B1 CLIA Kit
异质核蛋白A2/B1
货号:
U1024h
商标:
EIAab®
监管等级:
别名:
hnRNP A2/B1, HNRPA2B1
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
39-2500pg/mL
特异性:
Natural and recombinant human Heterogeneous nuclear ribonucleoproteins A2/B1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Epigenetics
通用注释
亚单元:
Identified in the spliceosome C complex (PubMed:11991638). Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs (PubMed:17289661). Interacts with IGF2BP1 (PubMed:17289661). Interacts with C9orf72 (PubMed:24549040). Interacts with DGCR8 (PubMed:26321680). Interacts with TARDBP (PubMed:19429692). Interacts with CKAP5 (PubMed:15703215).
功能:
(Microbial infection) Involved in the transport of HIV-1 genomic RNA out of the nucleus, to the microtubule organizing center (MTOC), and then from the MTOC to the cytoplasm: acts by specifically recognizing and binding the A2RE (21 nucleotide hnRNP A2 response element) sequence motifs present on HIV-1 genomic RNA, and promotes its transport.
亚细胞位置:
Isoform A2
Nucleus
Cytoplasm
Predominantly nucleoplasmic, however is also found in the cytoplasm of cells in some tissues (PubMed:17289661).
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