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Rab3gap1 (基因名), Rab3 GTPase-activating protein catalytic subunit (蛋白名), rb3gp_mouse.

产品名称:

Mouse Rab3gap1/ Rab3 GTPase-activating protein catalytic subunit CLIA Kit

货号:

商标:

EIAab^®

监管等级:

RUO

别名:

RAB3 GTPase-activating protein 130 kDa subunit, Rab3-GAP p130, Rab3-GAP, Kiaa0066, Rab3gap

检测方法:

CLIA

特异性:

Natural and recombinant mouse Rab3 GTPase-activating protein catalytic subunit

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

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Mouse Rab3gap1 CLIA Kit

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通用注释

亚单元:

The Rab3 GTPase-activating complex is a heterodimer composed of RAB3GAP and RAB3-GAP150. The Rab3 GTPase-activating complex interacts with DMXL2.

功能:

Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.

亚细胞位置:

Cytoplasm In neurons, it is enriched in the synaptic soluble fraction.

数据库链接

UniGene:

Mm.489713

STRING:

10090.ENSMUSP00000042070

KEGG:

mmu:226407

Pfam:

PF13890

Uniprot: