RAB14 (基因名), Ras-related protein Rab-14 (蛋白名), rab14_human.
产品名称:
Human RAB14/ Ras-related protein Rab-14 CLIA Kit
Ras相关蛋白Rab-14
货号:
U14990h
商标:
EIAab®
监管等级:
检测方法:
CLIA
特异性:
Natural and recombinant human Ras-related protein Rab-14
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Signal Transduction
通用注释
亚单元:
Interacts with KIF16B (By similarity). Interacts with ZFYVE20.
功能:
Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion.
亚细胞位置:
Recycling endosome
Early endosome membrane
Lipid-anchor
Cytoplasmic side
Golgi apparatus membrane
Lipid-anchor
Cytoplasmic side
Golgi apparatus
Trans-Golgi network membrane
Lipid-anchor
Cytoplasmic side
Cytoplasmic vesicle
Phagosome
Recruited to recycling endosomes by DENND6A (PubMed:22595670). Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211).
该产品尚未在任何出版物中被引用。
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