PRPF3 (基因名), U4/U6 small nuclear ribonucleoprotein Prp3 (蛋白名), prpf3_human.
产品名称:
Human PRPF3/ U4/U6 small nuclear ribonucleoprotein Prp3 CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
Pre-mRNA-splicing factor 3, U4/U6 snRNP 90 kDa protein, hPrp3, HPRP3, PRP3
检测方法:
CLIA
特异性:
Natural and recombinant human U4/U6 small nuclear ribonucleoprotein Prp3
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts directly with PRPF4. Part of a heteromeric complex containing PPIH, PRPF3 and PRPF4 that is stable in the absence of RNA. Component of the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, SNRNP40, DDX23, CD2BP2, PPIH, SNU13, EFTUD2, SART1 and USP39. Interacts with SART3; the interaction is direct and recruits the deubiquitinase USP4 to PRPF3. Interacts with PRPF19. Interacts ('Lys-63'-linked polyubiquitinated) with PRPF8 (via the MPN (JAB/Mov34) domain); may stabilize the U4/U6-U5 tri-snRNP complex.
功能:
Participates in pre-mRNA splicing. Part of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome.
亚细胞位置:
Nucleus speckle
Colocalizes with spliceosomal snRNPs.
数据库链接
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