Prpf6 (基因名), Pre-mRNA-processing factor 6 (蛋白名), prp6_rat.
产品名称:
Rat Prpf6/ Pre-mRNA-processing factor 6 CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
PRP6 homolog, U5 snRNP-associated 102 kDa protein, U5-102 kDa protein
检测方法:
CLIA
特异性:
Natural and recombinant rat Pre-mRNA-processing factor 6
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Associates with the U5 snRNP particle. Component of the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, SNRNP40, DDX23, CD2BP2, PPIH, SNU13, EFTUD2, SART1 and USP39, LSm proteins LSm2-8 and Sm proteins (By similarity). Interacts with ARAF1. Identified in the spliceosome C complex (By similarity). Interacts with AR and NR3C1, but not ESR1, independently of the presence of hormones.
功能:
Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation.
亚细胞位置:
Nucleus
Nucleoplasm
Nucleus speckle
Localized in splicing speckles.
数据库链接
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