Human PRPF6/ Pre-mRNA-processing factor 6 CLIA Kit

货号:

商标:

EIAab^®

监管等级:

RUO

别名:

Androgen receptor N-terminal domain-transactivating protein 1, PRP6 homolog, U5 snRNP-associated 102 kDa protein, ANT-1, U5-102 kDa protein, C20orf14

检测方法:

CLIA

特异性:

Natural and recombinant human Pre-mRNA-processing factor 6

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

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Human PRPF6 CLIA Kit

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通用注释

亚单元:

Associates with the U5 snRNP particle. Component of the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, SNRNP40, DDX23, CD2BP2, PPIH, SNU13, EFTUD2, SART1 and USP39, LSm proteins LSm2-8 and Sm proteins. Interacts with ARAF1. Identified in the spliceosome C complex. Interacts with AR and NR3C1, but not ESR1, independently of the presence of hormones.

功能:

Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation.

亚细胞位置:

Nucleus Nucleoplasm Nucleus speckle Localized in splicing speckles.

数据库链接

UniGene:

Hs.31334

SMR:

O94906

STRING:

9606.ENSP00000266079

KEGG:

hsa:24148

MIM: