Prpf40a (基因名), Pre-mRNA-processing factor 40 homolog A (蛋白名), pr40a_mouse.
产品名称:
Mouse Prpf40a/ Pre-mRNA-processing factor 40 homolog A CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
Formin-binding protein 11, Formin-binding protein 3, FBP-11, Fbp11, Fnbp3
检测方法:
CLIA
特异性:
Natural and recombinant mouse Pre-mRNA-processing factor 40 homolog A
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with the N-terminus of HTT and with the phosphorylated C-terminal domain of POLR2A (By similarity). Interacts with AKAP8L, SF1, SRPK1, CARD8, ATBF1 and MECP2. Interacts through the WW domains with formin proline-rich regions and with WASL/N-WASP.
功能:
Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing.
亚细胞位置:
Nucleus speckle
Nucleus matrix
Colocalizes with AKAP8L in the nuclear matrix.
数据库链接
验证序列:
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