Ptgs2 (基因名), Prostaglandin G/H synthase 2 (蛋白名), pgh2_mouse.
产品名称:
Mouse Ptgs2/ Prostaglandin G/H synthase 2 CLIA Kit
前列腺素G/H合成酶2
货号:
U0699m
商标:
EIAab®
监管等级:
别名:
Cyclooxygenase-2, Glucocorticoid-regulated inflammatory cyclooxygenase, Gripghs, Macrophage activation-associated marker protein P71/73, PES-2, PHS II, Prostaglandin H2 synthase 2, Prostaglandin-endoperoxide synthase 2, TIS10 protein, COX-2, PGH synthase 2, Cox-2, Cox2, Pghs-b, Tis10
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
39-2500pg/mL
特异性:
Natural and recombinant mouse Prostaglandin G/H synthase 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
Cardiovascular
通用注释
亚单元:
Homodimer.
功能:
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.
亚细胞位置:
Microsome membrane
Peripheral membrane protein
Endoplasmic reticulum membrane
Peripheral membrane protein
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