HCRT (基因名), Orexin (蛋白名), orex_canfa.
通用注释
亚单元:
N/A
功能:
Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity.
亚细胞位置:
Rough endoplasmic reticulum
Cytoplasmic vesicle
Cell junction
synapse
Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses.
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