Oprk1 (基因名), Kappa-type opioid receptor (蛋白名), oprk_mouse.
产品名称:
Mouse Oprk1/ Kappa-type opioid receptor CLIA Kit
Kappa-type阿片受体
货号:
U9978m
商标:
EIAab®
监管等级:
别名:
MSL-1, K-OR-1
检测方法:
CLIA
特异性:
Natural and recombinant mouse Kappa-type opioid receptor
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with SLC9A3R1. Interacts with GABARAPL1.
功能:
G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
亚细胞位置:
Cell membrane
Multi-pass membrane protein
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