OMA1 (基因名), Metalloendopeptidase OMA1, mitochondrial (蛋白名), oma1_human.
产品名称:
Human OMA1/ Metalloendopeptidase OMA1, mitochondrial CLIA Kit
货号:
U7661h
商标:
EIAab®
监管等级:
别名:
Metalloprotease-related protein 1, Overlapping with the m-AAA protease 1 homolog, MPRP-1, MPRP1
检测方法:
CLIA
特异性:
Natural and recombinant human Metalloendopeptidase OMA1, mitochondrial
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
N/A
功能:
Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.
亚细胞位置:
Mitochondrion inner membrane
Multi-pass membrane protein
数据库链接
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