Olfm4 (基因名), Olfactomedin-4 (蛋白名), olfm4_mouse.
通用注释
亚单元:
Homomultimer; disulfide-linked. Interacts with NDUFA13. Interacts with cell surface lectins (locutions ricinus communis agglutinin I, concanavalin A and wheat germ agglutinin) and cadherin.
功能:
May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin.
亚细胞位置:
Secreted
Extracellular space
Mitochondrion
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