Mmp2 (基因名), 72 kDa type IV collagenase (蛋白名), mmp2_mouse.
产品名称:
Mouse Mmp2/ 72 kDa type IV collagenase CLIA Kit
基质金属蛋白酶2/明胶酶A
货号:
U0100m
商标:
EIAab®
监管等级:
别名:
72 kDa gelatinase, Gelatinase A, Matrix metalloproteinase-2, MMP-2
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
39-2500pg/mL
特异性:
Natural and recombinant mouse 72 kDa type IV collagenase
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cancer
通用注释
亚单元:
Interacts (via the C-terminal hemopexin-like domains-containing region) with the integrin alpha-V/beta-3; the interaction promotes vascular invasion in angiogenic vessels and melamoma cells. Interacts (via the C-terminal PEX domain) with TIMP2 (via the C-terminal); the interaction inhibits the degradation activity. Interacts with GSK3B.
功能:
Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.
亚细胞位置:
Isoform 2
Cytoplasm
Mitochondrion
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