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Eef1e1 (基因名), Eukaryotic translation elongation factor 1 epsilon-1 (蛋白名), mca3_mouse.

产品名称:

Mouse Eef1e1/ Eukaryotic translation elongation factor 1 epsilon-1 CLIA Kit

货号:

U11479m

商标:

EIAab^®

监管等级:

RUO

别名:

Elongation factor p18, Multisynthase complex auxiliary component p18

检测方法:

CLIA

特异性:

Natural and recombinant mouse Eukaryotic translation elongation factor 1 epsilon-1

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cancer

规格 & 价格:

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通用注释

亚单元:

Component of the multisynthase complex which is comprised of a bifunctional glutamyl-prolyl-tRNA synthase, the monospecific isoleucyl, leucyl, glutaminyl, methionyl, lysyl, arginyl and aspartyl-tRNA synthases, and three auxiliary proteins, EEF1E1/p18, AIMP2/p38 and AIMP1/p43. Interacts with ATM and ATR. The interaction with ATM, which takes place independently of TP53, is induced by DNA damage that may occur during genotoxic stress or cell growth. The interaction with ATR is enhanced by UV irradiation.

功能:

Positive modulator of ATM response to DNA damage.

亚细胞位置:

Cytoplasm Nucleus Cytoplasmic under growth arrest conditions. Translocated into the nucleus when growth resumes at S phase and following DNA damage.

数据库链接

UniGene:

Mm.490319

SMR:

Q9D1M4

STRING:

10090.ENSMUSP00000001757

KEGG: