LTN1 (基因名), E3 ubiquitin-protein ligase listerin (蛋白名), ltn1_human.
产品名称:
Human LTN1/ E3 ubiquitin-protein ligase listerin CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
RING finger protein 160, RING-type E3 ubiquitin transferase listerin, Zinc finger protein 294, HSPC087, C21orf10, C21orf98, KIAA0714, RNF160, ZNF294
检测方法:
CLIA
特异性:
Natural and recombinant human E3 ubiquitin-protein ligase listerin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Component of the ribosome quality control complex (RQC), composed of at least the E3 ubiquitin ligase LTN1 and NEMF (PubMed:25578875). The complex probably also contains TCF25 as well as VCP/p97 and its ubiquitin-binding cofactors (By similarity). RQC forms a stable complex with 60S ribosomal subunits (PubMed:25578875).
功能:
E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:23685075, PubMed:25132172, PubMed:25578875). Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product.
亚细胞位置:
N/A
数据库链接
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