KLF17 (基因名), Krueppel-like factor 17 (蛋白名), klf17_pig.
通用注释
亚单元:
N/A
功能:
Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.
亚细胞位置:
Nucleus
数据库链接
验证序列:
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