KDM5D (基因名), Lysine-specific demethylase 5D (蛋白名), kdm5d_canlf.
产品名称:
Dog KDM5D/ Lysine-specific demethylase 5D CLIA Kit
Lysine-specific demethylase 5 d
货号:
U12893d
商标:
EIAab®
监管等级:
别名:
Histone demethylase JARID1D, Jumonji/ARID domain-containing protein 1D, Protein SmcY, JARID1D, SMCY
检测方法:
CLIA
特异性:
Natural and recombinant dog Lysine-specific demethylase 5D
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts withPCGF6, MSH5, ZMYND8, AR.
功能:
Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis. Involved in transcriptional repression of diverse metastasis-associated genes; in this function seems to cooperate with ZMYND8. Suppresses prostate cancer cell invasion. Regulates androgen receptor (AR) transcriptional activity by demethylating H3K4me3 active transcription marks.
亚细胞位置:
Nucleus
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