Kcnq2 (基因名), Potassium voltage-gated channel subfamily KQT member 2 (蛋白名), kcnq2_rat.
产品名称:
Rat Kcnq2/ Potassium voltage-gated channel subfamily KQT member 2 CLIA Kit
钾电压门控通道亚家族KQT成员2
货号:
U2348r
商标:
EIAab®
监管等级:
别名:
KQT-like 2, Potassium channel subunit alpha KvLQT2, Voltage-gated potassium channel subunit Kv7.2
检测方法:
CLIA
特异性:
Natural and recombinant rat Potassium voltage-gated channel subfamily KQT member 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Neurosciences
通用注释
亚单元:
Heteromultimer with KCNQ3.
功能:
Probably important in the regulation of neuronal excitability. Associates with KCNQ3 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs. KCNQ2 current is blocked by barium and tetraethylammonium whereas 4-aminopyridine and charybdotoxin have no effect on KCNQ2 current. Tyrosine kinase inhibitors genistein or herbimycin a markedly down-regulate KCNQ2 current. Muscarinic agonist oxotremorine-M suppress KCNQ2/KCNQ3 current in CHO cells in which cloned KCNQ2/KCNQ3 channels were coexpressed with human M1 muscarinic receptors.
亚细胞位置:
Membrane
Multi-pass membrane protein
数据库链接
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