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Kcne3 (基因名), Potassium voltage-gated channel subfamily E member 3 (蛋白名), kcne3_mouse.

产品名称:

Mouse Kcne3/ Potassium voltage-gated channel subfamily E member 3 CLIA Kit

货号:

商标:

EIAab^®

监管等级:

RUO

别名:

MinK-related peptide 2, Minimum potassium ion channel-related peptide 2, Potassium channel subunit beta MiRP2

检测方法:

CLIA

特异性:

Natural and recombinant mouse Potassium voltage-gated channel subfamily E member 3

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

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Mouse Kcne3 CLIA Kit

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通用注释

亚单元:

Interacts with KCNB1. Interacts with KCNC2 (By similarity). Associates with KCNC4/Kv3.4 (By similarity). Interacts with KCNQ1; produces a current with nearly instantaneous activation with a linear current-voltage relationship and alters membrane raft localization.

功能:

Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Associated with KCNC4/Kv3.4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion that produces a current with nearly instantaneous activation with a linear current-voltage relationship.

亚细胞位置:

Cell membrane Single-pass type I membrane protein Cytoplasm Perikaryon Cell projection Dendrite Membrane raft Colocalizes with KCNB1 at high-density somatodendritic clusters on the surface of hippocampal neurons.

数据库链接

UniGene:

Mm.282386

SMR:

Q9WTW2

STRING:

10090.ENSMUSP00000039353

KEGG:

mmu:57442

Pfam:

PF02060

Uniprot:

Q9WTW2