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KCNC1 (基因名), Potassium voltage-gated channel subfamily C member 1 (蛋白名), kcnc1_human.

产品名称:

Human KCNC1/ Potassium voltage-gated channel subfamily C member 1 CLIA Kit

货号:

U2326h

商标:

EIAab^®

监管等级:

RUO

别名:

NGK2, Voltage-gated potassium channel subunit Kv3.1, Voltage-gated potassium channel subunit Kv4

检测方法:

CLIA

特异性:

Natural and recombinant human Potassium voltage-gated channel subfamily C member 1

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Human KCNC1 CLIA Kit

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通用注释

亚单元:

Heteromultimer with KCNG3, KCNG4 and KCNV2 (By similarity). Heteromultimer with KCNC2 (By similarity). Heterotetramer with KCNC3 (PubMed:23734863). Interacts with the ancillary subunits KCNE1 and KCNE2; the interaction modulates channel activity.

功能:

Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. The channel opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient (PubMed:25401298). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well. Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons.

亚细胞位置:

Cell membrane Multi-pass membrane protein

数据库链接

UniGene:

Hs.552896

SMR:

P48547

STRING:

9606.ENSP00000265969

KEGG:

hsa:3746

MIM: