Kcnj16 (基因名), Inward rectifier potassium channel 16 (蛋白名), kcj16_mouse.
产品名称:
Mouse Kcnj16/ Inward rectifier potassium channel 16 CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
Inward rectifier K(+) channel Kir5.1, Potassium channel, inwardly rectifying subfamily J member 16
检测方法:
CLIA
特异性:
Natural and recombinant mouse Inward rectifier potassium channel 16
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
-
通用注释
亚单元:
Heterodimer with Kir4.1/KCNJ10; this interaction is required for KCNJ16 localization to the basolateral membrane in kidney cells. As a heterodimer with KCNJ10, may interact with MAGI1; this interaction may facilitate KCNJ10/KCNJ16 potassium channel expression at the basolateral membrane in kidney cells. May form heterodimers with Kir2.1/KCNJ2.
功能:
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance. In the kidney, together with KCNJ10, mediates basolateral K(+) recycling in distal tubules; this process is critical for Na(+) reabsorption at the tubules.
亚细胞位置:
Membrane
Multi-pass membrane protein
Basolateral cell membrane
In kidney distal convoluted tubules, located in the basolateral membrane in the presence of KCNJ10.
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