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KCNJ12 (基因名), ATP-sensitive inward rectifier potassium channel 12 (蛋白名), kcj12_bovin.

产品名称:

Bovine KCNJ12/ ATP-sensitive inward rectifier potassium channel 12 CLIA Kit

货号:

U5743b

商标:

EIAab^®

监管等级:

RUO

别名:

Potassium channel, inwardly rectifying subfamily J member 12

检测方法:

CLIA

特异性:

Natural and recombinant bovine ATP-sensitive inward rectifier potassium channel 12

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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通用注释

亚单元:

Homotetramer. Forms heteromer with KCNJ4. Association, via its PDZ-recognition domain, with LIN7A, LIN7B, LIN7C, DLG1, CASK and APBA1 plays a key role in its localization and trafficking.

功能:

Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

亚细胞位置:

Membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein

数据库链接

UniGene:

Bt.46903

SMR:

Q4TZY1

STRING:

9913.ENSBTAP00000056563

Pfam:

PF01007

Uniprot: