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Kcnj11 (基因名), ATP-sensitive inward rectifier potassium channel 11 (蛋白名), kcj11_rat.

产品名称:

Rat Kcnj11/ ATP-sensitive inward rectifier potassium channel 11 CLIA Kit

货号:

商标:

EIAab^®

监管等级:

RUO

别名:

BIR, Inward rectifier K(+) channel Kir6.2, Potassium channel, inwardly rectifying subfamily J member 11

检测方法:

CLIA

特异性:

Natural and recombinant rat ATP-sensitive inward rectifier potassium channel 11

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

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通用注释

亚单元:

Interacts with ABCC9/SUR2 (By similarity). Interacts with ABCC8/SUR.

功能:

This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.

亚细胞位置:

Membrane Multi-pass membrane protein

数据库链接

UniGene:

Rn.3985

SMR:

P70673

STRING:

10116.ENSRNOP00000028685

KEGG:

rno:83535

Pfam: