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Camk2g (基因名), Calcium/calmodulin-dependent protein kinase type II subunit gamma (蛋白名), kcc2g_mouse.

产品名称:

Mouse Camk2g/ Calcium/calmodulin-dependent protein kinase type II subunit gamma CLIA Kit

货号:

商标:

EIAab^®

监管等级:

RUO

别名:

CaM kinase II subunit gamma

检测方法:

CLIA

特异性:

Natural and recombinant mouse Calcium/calmodulin-dependent protein kinase type II subunit gamma

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cardiovascular

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通用注释

亚单元:

CAMK2 is composed of 4 different chains: alpha (CAMK2A), beta (CAMK2B), gamma (CAMK2G), and delta (CAMK2D). The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 12 subunits with two hexameric rings stacked one on top of the other.

功能:

Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplasmic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.

亚细胞位置:

Sarcoplasmic reticulum membrane Peripheral membrane protein Cytoplasmic side

数据库链接

UniGene:

Mm.235182

SMR:

Q923T9

STRING:

10090.ENSMUSP00000071720

KEGG:

mmu:12325

Pfam: