Kat6a (基因名), Histone acetyltransferase KAT6A (蛋白名), kat6a_mouse.
产品名称:
Mouse Kat6a/ Histone acetyltransferase KAT6A CLIA Kit
组蛋白乙酰转移酶KAT6A
货号:
U2936m
商标:
EIAab®
监管等级:
别名:
MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3, Monocytic leukemia zinc finger homolog, Monocytic leukemia zinc finger protein, MYST-3, Moz, Myst3
检测方法:
CLIA
特异性:
Natural and recombinant mouse Histone acetyltransferase KAT6A
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
-
通用注释
亚单元:
Component of the MOZ/MORF complex composed at least of ING5, KAT6A, KAT6B, MEAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3 (By similarity). Interacts with RUNX2 (By similarity). Interacts with RUNX1; phosphorylation of RUNX1 enhances the interaction. Interacts with p53/TP53 (By similarity). Interacts with PML and this interaction positively regulates its acetylation activity towards p53/TP53.
功能:
Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2 (By similarity). Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML.
亚细胞位置:
Nucleus
Nucleus
Nucleolus
Nucleus
Nucleoplasm
Nucleus
PML body
Recruited into PML body after DNA damage.
验证序列:
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