KRT18 (基因名), Keratin, type I cytoskeletal 18 (蛋白名), k1c18_human.
产品名称:
Human KRT18/ Keratin, type I cytoskeletal 18 CLIA Kit
角蛋白细胞骨架18型
货号:
U1231h
商标:
EIAab®
监管等级:
别名:
Cell proliferation-inducing gene 46 protein, Cytokeratin-18, Keratin-18, CK-18, K18, PIG46, CYK18
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
7.8-500pg/mL
特异性:
Natural and recombinant human Keratin, type I cytoskeletal 18
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Epigenetics
通用注释
亚单元:
Heterotetramer of two type I and two type II keratins. KRT18 associates with KRT8. Interacts with the thrombin-antithrombin complex (By similarity). Interacts with PNN, HCV core protein and mutated CFTR. Interacts with YWHAE, YWHAH and YWHAZ only when phosphorylated. Interacts with DNAJB6, TCHP and TRADD. Interacts with FAM83H (PubMed:23902688). Interacts with EPPK1.
功能:
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
亚细胞位置:
Cytoplasm
Perinuclear region
Nucleus
Nucleolus
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