Dog KCNJ2/ Inward rectifier potassium channel 2 CLIA Kit

货号:

商标:

EIAab^®

监管等级:

RUO

别名:

Cardiac inward rectifier potassium channel, Inward rectifier K(+) channel Kir2.1, Potassium channel, inwardly rectifying subfamily J member 2, IRK-1, IRK1

检测方法:

CLIA

特异性:

Natural and recombinant dog Inward rectifier potassium channel 2

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

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Dog KCNJ2 CLIA Kit

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通用注释

亚单元:

Homomultimeric and heteromultimeric association with Kir2.3, resulting in an enhanced G-protein-induced current. Association, via its PDZ-recognition domain, with LIN7A, LIN7B, LIN7C, DLG1, CASK and APBA1 plays a key role in its localization and trafficking.

功能:

Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Blocked by external barium or cesium.

亚细胞位置:

Membrane Multi-pass membrane protein

数据库链接

Uniprot:

Q9MYY9

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