Ireb2 (基因名), Iron-responsive element-binding protein 2 (蛋白名), ireb2_rat.
产品名称:
Rat Ireb2/ Iron-responsive element-binding protein 2 CLIA Kit
铁反应元件结合蛋白2
货号:
U13568r
商标:
EIAab®
监管等级:
别名:
Iron regulatory protein 2, IRP2, IRE-BP 2, Irp2
检测方法:
CLIA
实验类型:
Sandwich
特异性:
Natural and recombinant rat Iron-responsive element-binding protein 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with RBCK1 only in iron-rich conditions. Interacts (when associated with the 4Fe-4S) with FBXL5.
功能:
RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
亚细胞位置:
Cytoplasm
数据库链接
验证序列:
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