Intu (基因名), Protein inturned (蛋白名), intu_rat.
产品名称:
Rat Intu/ Protein inturned CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
Inturned planar cell polarity effector homolog, PDZ domain-containing protein 6, Pdzd6
检测方法:
CLIA
特异性:
Natural and recombinant rat Protein inturned
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
N/A
功能:
Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies.
亚细胞位置:
Cytoplasm
Cell surface
Cytoplasm
Cytoskeleton
Cilium basal body
Enriched at the apical surface in ciliated cells.
验证序列:
该产品尚未在任何出版物中被引用。
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