Human IFNAR2/ Interferon alpha/beta receptor 2 CLIA Kit
干扰素α/β受体2

货号:

U1101h

商标:

EIAab^®

监管等级:

RUO

别名:

Interferon alpha binding protein, Type I interferon receptor 2, IFN-R-2, IFNABR, IFNARB

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

0.2-12.5ng/mL

特异性:

Natural and recombinant human Interferon alpha/beta receptor 2

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Immunology

规格 & 价格:

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Human IFNAR2 CLIA Kit

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
序列 / 3D
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通用注释

亚单元:

Heterodimer with IFNAR1 (PubMed:8181059, PubMed:7665574, PubMed:10049744, PubMed:24075985, PubMed:21854986). Isoform 1 interacts with the transcriptional factors STAT1 and STAT2 (PubMed:9121453). Interacts with JAK1 (PubMed:8181059, PubMed:7759950).

功能:

Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation (PubMed:26424569). Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1 (PubMed:8181059, PubMed:7665574, PubMed:7759950). Isoform 3 is a potent inhibitor of type I IFN receptor activity (PubMed:7759950).

亚细胞位置:

Isoform 3 Secreted

数据库链接

UniGene:

Hs.708195

SMR:

P48551

STRING:

9606.ENSP00000343957

KEGG:

hsa:3455

MIM: