Mouse Ifitm1/ Interferon-induced transmembrane protein 1 CLIA Kit
干扰素诱导跨膜蛋白1

货号:

U15511m

商标:

EIAab^®

监管等级:

RUO

别名:

Dispanin subfamily A member 2a, Fragilis protein 2, Mouse ifitm-like protein 2, DSPA2a, Mil-2

检测方法:

CLIA

特异性:

Natural and recombinant mouse Interferon-induced transmembrane protein 1

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cancer

规格 & 价格:

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Mouse Ifitm1 CLIA Kit

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通用注释

亚单元:

Interacts with CAV1; this interaction enhances the ability of CAV1 in inhibiting ERK activation. Interacts with CD81.

功能:

IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV) and West Nile virus (WNV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation.

亚细胞位置:

Cell membrane Single-pass membrane protein

数据库链接

UniGene:

Mm.175661

STRING:

10090.ENSMUSP00000026564

KEGG:

mmu:68713

Pfam:

PF04505

Uniprot: