Rat Id1/ DNA-binding protein inhibitor ID-1 CLIA Kit
dna结合蛋白抑制剂ID-1

货号:

U15416r

商标:

EIAab^®

监管等级:

RUO

别名:

Inhibitor of DNA binding 1, Inhibitor of differentiation 1, Id-1

检测方法:

CLIA

特异性:

Natural and recombinant rat DNA-binding protein inhibitor ID-1

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Rat Id1 CLIA Kit

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通用注释

亚单元:

Heterodimer with other HLH proteins. Interacts with COPS5, IFI204, GATA4, NKX2-5, CLOCK and ARNTL/BMAL1 (By similarity). Isoform Short can form homodimers.

功能:

Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer.

亚细胞位置:

Cytoplasm Nucleus

数据库链接

UniGene:

Rn.2113

SMR:

P41135

STRING:

10116.ENSRNOP00000052261

KEGG:

rno:25261

Pfam: