Rat Icos/ Inducible T-cell costimulator CLIA Kit
诱导t细胞costimulator

货号:

U15375r

商标:

EIAab^®

监管等级:

RUO

别名:

Activation-inducible lymphocyte immunomediatory molecule, CD278, Ailim

检测方法:

CLIA

特异性:

Natural and recombinant rat Inducible T-cell costimulator

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Rat Icos CLIA Kit

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通用注释

亚单元:

Homodimer; disulfide-linked.

功能:

Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.

亚细胞位置:

Membrane Single-pass type I membrane protein

数据库链接

UniGene:

Rn.168816

SMR:

Q9R1T7

STRING:

10116.ENSRNOP00000064455

KEGG:

rno:64545

Pfam: