Icos (基因名), Inducible T-cell costimulator (蛋白名), icos_mouse.
产品名称:
Mouse Icos/ Inducible T-cell costimulator CLIA Kit
诱导t细胞costimulator
货号:
U15375m
商标:
EIAab®
监管等级:
别名:
Activation-inducible lymphocyte immunomediatory molecule, CD28 and CTLA-4-like protein, CD28-related protein 1, CCLP, CRP-1, CD278, Ailim
检测方法:
CLIA
特异性:
Natural and recombinant mouse Inducible T-cell costimulator
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Homodimer; disulfide-linked.
功能:
Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
亚细胞位置:
Membrane
Single-pass type I membrane protein
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