Ick (基因名), Serine/threonine-protein kinase ICK (蛋白名), ick_rat.
产品名称:
Rat Ick/ Serine/threonine-protein kinase ICK CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
Intestinal cell kinase, MAK-related kinase, MRK
检测方法:
CLIA
特异性:
Natural and recombinant rat Serine/threonine-protein kinase ICK
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cancer
通用注释
亚单元:
N/A
功能:
Required for ciliogenesis, particularly in neuronal and retinal progenitor cells (By similarity). Phosphorylates KIF3A (By similarity). Involved in the control of ciliary length (By similarity). Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity). May play a role in cardiac development (PubMed:8570168). Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner and this regulation requires its kinase activity.
亚细胞位置:
Cytoplasm
Cell projection
Cilium
Nucleus
Cytoplasm
Cytoskeleton
Cilium basal body
Also found at the ciliary tip.
数据库链接
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