IGFBP3 (基因名), Insulin-like growth factor-binding protein 3 (蛋白名), ibp3_pig.
产品名称:
Pig IGFBP3/ Insulin-like growth factor-binding protein 3 CLIA Kit
类胰岛素生长因子结合蛋白3
货号:
U0054p
商标:
EIAab®
监管等级:
别名:
IBP-3
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
0.39-25ng/mL
特异性:
Natural and recombinant pig Insulin-like growth factor-binding protein 3
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
Cancer
通用注释
亚单元:
Interacts with XLKD1. Binds IGF2 more than IGF1. Forms a ternary complex of about 140 to 150 kDa with IGF1 or IGF2 and a 85 kDa glycoprotein (ALS). Interacts with HN. Interacts with TMEM219.
功能:
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.
亚细胞位置:
Secreted
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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