Rat Irf2bpl/ Probable E3 ubiquitin-protein ligase IRF2BPL CLIA Kit

货号:

商标:

EIAab^®

监管等级:

RUO

别名:

Enhanced at puberty protein 1, Interferon regulatory factor 2-binding protein-like, Polyglutamine-containing protein, Eap1, Pqcp

检测方法:

CLIA

特异性:

Natural and recombinant rat Probable E3 ubiquitin-protein ligase IRF2BPL

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

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Rat Irf2bpl CLIA Kit

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通用注释

亚单元:

Interacts with CTNNB1.

功能:

Probable E3 ubiquitin protein ligase involved in the proteasome-mediated ubiquitin-dependent degradation of target proteins. Through the degradation of CTNNB1, functions downstream of FOXF2 to negatively regulate the Wnt signaling pathway. Probably plays a role in the development of the central nervous system and in neuronal maintenance (By similarity). Also acts as a transcriptional regulator of genes controlling female reproductive function. May play a role in gene transcription by transactivating GNRH1 promoter and repressing PENK promoter.

亚细胞位置:

Nucleus

数据库链接

UniGene:

Rn.15682

SMR:

Q5EIC4

STRING:

10116.ENSRNOP00000064525

KEGG:

rno:314329

Pfam: