Human HAS2/ Hyaluronan synthase 2 CLIA Kit
透明质酸合成酶2

货号:

U1143h

商标:

EIAab^®

监管等级:

RUO

别名:

Hyaluronate synthase 2, Hyaluronic acid synthase 2, HA synthase 2

检测方法:

CLIA

特异性:

Natural and recombinant human Hyaluronan synthase 2

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cardiovascular

规格 & 价格:

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Human HAS2 CLIA Kit

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亚单元:

N/A

功能:

Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction and it is particularly responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells into mesenchymal cells, a process crucial for heart development. May also play a role in vasculogenesis. High molecular mass hyaluronan also play a role in early contact inhibition a process which stops cell growth when cells come into contact with each other or the extracellular matrix.

亚细胞位置:

Membrane Multi-pass membrane protein

数据库链接

UniGene:

Hs.159226

STRING:

9606.ENSP00000306991

KEGG:

hsa:3037

MIM:

601636

Pfam: