Dog HSPA1/ Heat shock 70 kDa protein 1 CLIA Kit
热休克70 kDa蛋白

货号:

U0873d

商标:

EIAab^®

监管等级:

RUO

别名:

Hsp70

检测方法:

CLIA

特异性:

Natural and recombinant dog Heat shock 70 kDa protein 1

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Dog HSPA1 CLIA Kit

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产品说明书

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数据
文献
序列 / 3D
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通用注释

亚单元:

Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Interacts with IRAK1BP1, KTU and TSC2 (By similarity). Interacts with TERT; the interaction occurs in the absence of the RNA component, TERC, and dissociates once the TERT complex has formed (By similarity). Interacts with CHCHD3.

功能:

In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.

亚细胞位置:

Cytoplasm Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

数据库链接

Uniprot:

Q7YQC6

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