HSPH1 (基因名), Heat shock protein 105 kDa (蛋白名), hs105_bovin.
通用注释
亚单元:
Interacts with HSPA8/HSC70. Interacts with HSPA1A (via NBD) and HSPA1B (via NBD).
功能:
Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering substrate release. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.
亚细胞位置:
Cytoplasm
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
验证序列:
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