Dog HP/ Haptoglobin CLIA Kit

货号:

商标:

EIAab^®

监管等级:

RUO

检测方法:

CLIA

特异性:

Natural and recombinant dog Haptoglobin

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cardiovascular

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Dog HP CLIA Kit

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产品说明书

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通用注释

亚单元:

Tetramer of two alpha and two beta chains; disulfide-linked. The hemoglobin/haptoglobin complex is composed of a haptoglobin dimer bound to two hemoglobin alpha-beta dimers. Interacts with CD163 (By similarity).

功能:

As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway (By similarity).

亚细胞位置:

Secreted Extracellular space

数据库链接

SMR:

P19006

STRING:

9615.ENSCAFP00000029992

Pfam:

PF00089

Uniprot:

P19006

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