Hmgcr (基因名), 3-hydroxy-3-methylglutaryl-coenzyme A reductase (蛋白名), hmdh_mouse.
产品名称:
Mouse Hmgcr/ 3-hydroxy-3-methylglutaryl-coenzyme A reductase CLIA Kit
3-羟基3-methylglutaryl辅酶还原
货号:
U10451m
商标:
EIAab®
监管等级:
别名:
HMG-CoA reductase
检测方法:
CLIA
特异性:
Natural and recombinant mouse 3-hydroxy-3-methylglutaryl-coenzyme A reductase
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cardiovascular
通用注释
亚单元:
Homodimer. Interacts with INSIG1 (via its SSD); the interaction, accelerated by sterols, leads to the recruitment of HMGCR to AMFR/gp78 for its ubiquitination by the sterol-mediated ERAD pathway. Interacts with UBIAD1.
功能:
Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.
亚细胞位置:
Endoplasmic reticulum membrane
Multi-pass membrane protein
数据库链接
验证序列:
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