Bovine H2AFZ/ Histone H2A.Z CLIA Kit

货号:

商标:

EIAab^®

监管等级:

RUO

别名:

H2A/z, H2AZ

检测方法:

CLIA

特异性:

Natural and recombinant bovine Histone H2A.Z

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Epigenetics

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Bovine H2AFZ CLIA Kit

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产品说明书

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数据
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序列 / 3D
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通用注释

亚单元:

The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. H2A or its variant H2AFZ forms a heterodimer with H2B. H2AFZ interacts with INCENP. Interacts (via M6 cassette) with ANP32E; leading to removal of H2A.Z/H2AFZ from the nucleosome.

功能:

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.

亚细胞位置:

Nucleus Chromosome

数据库链接

UniGene:

Bt.2515

SMR:

P0C0S4

STRING:

9913.ENSBTAP00000022576

KEGG:

bta:287016

Pfam: