GHR (基因名), Growth hormone receptor (蛋白名), ghr_canfa.
产品名称:
Dog GHR/ Growth hormone receptor CLIA Kit
生长激素受体
货号:
U1036d
商标:
EIAab®
监管等级:
别名:
Somatotropin receptor, GH receptor
检测方法:
CLIA
特异性:
Natural and recombinant dog Growth hormone receptor
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cancer
通用注释
亚单元:
On growth hormone (GH) binding, forms homodimers and binds JAK2 via a box 1-containing domain (By similarity). Binding to SOCS3 inhibits JAK2 activation, binding to CIS and SOCS2 inhibits STAT5 activation.
功能:
The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.
亚细胞位置:
Cell membrane
Single-pass type I membrane protein
On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway.
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