Rat Ggt1/ Glutathione hydrolase 1 proenzyme CLIA Kit
γ谷氨酰转移酶1

货号:

U1375r

商标:

EIAab^®

监管等级:

RUO

别名:

Gamma-glutamyltransferase 1, Gamma-glutamyltranspeptidase 1, Leukotriene-C4 hydrolase, GGT 1, CD224, Ggt

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

0.195-12.5ng/mL

特异性:

Natural and recombinant rat Glutathione hydrolase 1 proenzyme

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cell Biology

规格 & 价格:

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产品说明书

说明书:

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通用注释

亚单元:

Heterodimer composed of the light and heavy chains. The active site is located in the light chain.

功能:

Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism.

亚细胞位置:

Cell membrane Single-pass type II membrane protein

数据库链接

UniGene:

Rn.10010

SMR:

P07314

KEGG:

rno:116568

Pfam:

PF01019

Uniprot: