Dog HSP90B1/ Endoplasmin CLIA Kit

货号:

商标:

EIAab^®

监管等级:

RUO

别名:

94 kDa glucose-regulated protein, Heat shock protein 90 kDa beta member 1, GRP-94, GRP94, TRA1

检测方法:

CLIA

特异性:

Natural and recombinant dog Endoplasmin

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cancer

关注

Dog HSP90B1 CLIA Kit

邮箱 *

消息 *

Please 登录.

产品说明书

在线询价

数据
文献
序列 / 3D
反馈墙 (0)

通用注释

亚单元:

Homodimer; disulfide-linked. Component of an EIF2 complex at least composed of CELF1/CUGBP1, CALR, CALR3, EIF2S1, EIF2S2, HSP90B1 and HSPA5 (By similarity). Part of a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX. Interacts with AIMP1; regulates its retention in the endoplasmic reticulum. Interacts with OS9 (By similarity). Interacts with CNPY3; this interaction is disrupted in the presence of ATP. Interacts with several TLRs, including TLR4 and TLR9, but not with TLR3 (By similarity). Interacts with MZB1 in a calcium-dependent manner (By similarity). Interacts with METTL23.

功能:

Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity.

亚细胞位置:

Endoplasmic reticulum lumen Sarcoplasmic reticulum Melanosome

数据库链接

UniGene:

Cfa.3896

SMR:

P41148

STRING:

9615.ENSCAFP00000011044

KEGG:

cfa:404019

Pfam: