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EIF3A (基因名), Eukaryotic translation initiation factor 3 subunit A (蛋白名), eif3a_human.

产品名称:

Human EIF3A/ Eukaryotic translation initiation factor 3 subunit A CLIA Kit
真核翻译起始因子3a

货号:

U1885h

商标:

EIAab^®

监管等级:

RUO

别名:

Eukaryotic translation initiation factor 3 subunit 10, eIF-3-theta, eIF3 p167, eIF3 p180, eIF3 p185, eIF3a, EIF3S10, KIAA0139

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

39-2500pg/mL

特异性:

Natural and recombinant human Eukaryotic translation initiation factor 3 subunit A

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Epigenetics

规格 & 价格:

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Human EIF3A CLIA Kit

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
序列 / 3D
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通用注释

亚单元:

Interacts with EIF4G1 (By similarity). Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3L and EIF3K. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Also interacts with KRT7 and PIWIL2.

功能:

(Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2 (PubMed:18056426).

亚细胞位置:

Cytoplasm

数据库链接

UniGene:

Hs.523299

SMR:

Q14152

STRING:

9606.ENSP00000358140

KEGG:

hsa:8661

MIM: