HSD17B12 (基因名), Very-long-chain 3-oxoacyl-CoA reductase (蛋白名), dhb12_bovin.
产品名称:
Bovine HSD17B12/ Very-long-chain 3-oxoacyl-CoA reductase CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
17-beta-hydroxysteroid dehydrogenase 12, 3-ketoacyl-CoA reductase, Estradiol 17-beta-dehydrogenase 12, 17-beta-HSD 12, KAR
检测方法:
CLIA
特异性:
Natural and recombinant bovine Very-long-chain 3-oxoacyl-CoA reductase
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
N/A
功能:
Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3-hydroxyacyl-CoA, within each cycle of fatty acid elongation. Thereby, it may participate in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation.
亚细胞位置:
Endoplasmic reticulum membrane
Multi-pass membrane protein
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